Lymphatics is the vascular system dedicated to drainage and filtration of interstitial fluid, carriage of fats after digestion, and interconnection of the lymphatic nodes. Therefore, when pathogens enter a tissue (e.g. through a cut), local acute inflammation (as part of the innate immune response) causes increased lymphatic permeability and enable some of the particles to be carried from the site of infection to a lymph node via the lymphatic system. A lymph node is an aggregation of lymphoid cells (T cells and B cells) in the periphery and initiates the adaptive immune response, which is more systematic and clears the infection more effectively.
Superficial lymphatics are located closer to the surface of the skin and drain lymph from the skin and underlying tissues, while deep lymphatics are located deeper within the body and drain lymph from the muscles, joints, and organs. Deep lymphatics also play a role in transporting lymph to the central lymphatic channels in the body.
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Lena Yew Yin Koh has written: 'Developmental and physiological insights into the role of lymphatics in cerebrospinal fluid absorption'
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