Fibrosis is repair. When a tissue is damaged fibroblasts repair the damage and this process is called Fibrosis.
fibrosis
fibrosis
Skin injuries typically heal using regeneration in which the dead or damaged cells are replaced by identical cells, while more severe injuries may heal using fibrosis. Fibrosis will not restore the function of the lost cells, however, the scar tissue is capable of holding the organ together. Therefore, regeneration is more desirable.
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skeletal muscle is made up of permanent cells - ie they never divide. this means if it is lost then it will heal by repair with organisation and progressive fibrosis = scar formation.
pulmonary fibrosis
Tissues that heal by scar tissue typically include dense connective tissues such as skin, tendons, and ligaments. In these tissues, the inflammatory response triggers the formation of scar tissue to repair the damage. However, the formation of scar tissue can lead to reduced functional capacity compared to the original tissue.
The abnormal formation of fibrous tissue is called fibrosis. It can occur in response to injury, inflammation, or other types of damage to tissues. Fibrosis can lead to stiffening and scarring of tissues, affecting their function.
Lumps in tissues can be caused by several types of fibrosis, but one common type is desmoplastic fibrosis, often associated with tumors. This condition leads to the formation of dense connective tissue, resulting in palpable lumps. Another example is cystic fibrosis, which can lead to the formation of fibrous tissue in organs like the lungs, although it typically presents more complex symptoms than just lumps. Overall, fibrosis can result in abnormal tissue growth, leading to lump formation in affected areas.
The two types of tissue repair are regeneration, where damaged tissue is replaced with new functional tissue, and fibrosis, where damaged tissue is replaced with scar tissue made of collagen fibers. Regeneration is ideal as it restores normal tissue function, while fibrosis can lead to loss of function depending on the extent of scarring.
Fibrosis is the formation of excess fibrous connective tissue in response to injury or inflammation, leading to scarring and stiffness in the affected area. Sclerosis, on the other hand, refers to the hardening or thickening of tissues, often due to the accumulation of substances like calcium. Both conditions can impair the normal function of tissues and organs, but fibrosis is more focused on the formation of scar tissue, while sclerosis involves the hardening of tissues.