Fibrosis is repair. When a tissue is damaged fibroblasts repair the damage and this process is called Fibrosis.
Tissue repair occurs primarily through regeneration and fibrosis. Regeneration involves the replacement of damaged cells with new cells of the same type, restoring normal function, while fibrosis involves the formation of scar tissue when regeneration is insufficient, often leading to a loss of function in the affected area. Both processes are essential for healing, depending on the type and extent of the injury.
Fibrosis is a pathological process characterized by the excessive accumulation of extracellular matrix components, primarily collagen, leading to scarring and tissue stiffening. While adipocytes (fat cells) can proliferate and play a role in tissue repair, fibrosis specifically refers to the formation of fibrous connective tissue, not the normal division of adipocytes. In some cases, when tissue is damaged, an imbalance between repair and degradation can lead to fibrosis, but this is distinct from the normal regenerative processes involving adipocytes.
fibrosis
fibrosis
Skin injuries typically heal using regeneration in which the dead or damaged cells are replaced by identical cells, while more severe injuries may heal using fibrosis. Fibrosis will not restore the function of the lost cells, however, the scar tissue is capable of holding the organ together. Therefore, regeneration is more desirable.
Tissue repair primarily occurs through regeneration and fibrosis. Regeneration involves the replacement of damaged cells with new, functional cells of the same type, restoring normal tissue architecture and function. In contrast, fibrosis occurs when the tissue is unable to regenerate fully, leading to the formation of scar tissue composed of collagen that may not fully restore the original functionality. Both processes are essential for healing but can vary depending on the type and extent of injury.
true
skeletal muscle is made up of permanent cells - ie they never divide. this means if it is lost then it will heal by repair with organisation and progressive fibrosis = scar formation.
Tissues that heal by scar tissue typically include dense connective tissues such as skin, tendons, and ligaments. In these tissues, the inflammatory response triggers the formation of scar tissue to repair the damage. However, the formation of scar tissue can lead to reduced functional capacity compared to the original tissue.
pulmonary fibrosis
The abnormal formation of fibrous tissue is called fibrosis. It can occur in response to injury, inflammation, or other types of damage to tissues. Fibrosis can lead to stiffening and scarring of tissues, affecting their function.