Zade Lunat
*the advantage is that it is the only viable source of clinical quantities of human insulin. Before it's FDA approval for Genetech patients would inject animal insulin purified from animal tissue. Disadvantages? From the frame of mind that is the ONLY source of externally provided human insulin it is hard to attribute disadvantages.
Type I diabetes that cannot be successfully treated with animal insulin.
The world's first genetically engineered pharmaceutical product was Humulin, approved by the FDA in 1982. Humulin is a synthetic form of human insulin that is produced using genetically modified bacteria to help manage diabetes.
Apart from idealogical concerns there shouldn't be any. Genetically engineered insulin is much, much safer than extracting insulin from pig's panreas as they did before they isolated the human insulin gene.
Insulin
When insulin was being commercially produced in genetically engineered bacteria and yeast, it was obtained from the pancreas of pigs and cows. This animal insulin was then purified and used as a template to create synthetic human insulin through genetic engineering processes.
Advantages * Cheaper to be made then by normal methods * the E.coli bacteria are friendly to the body * bacteria can be placed in yoghurt- 1-3 yoghurt's a day should be all you would need * bacteria can produce exact amount of insulin needed in response to the host's needs * no allergy problems - using pig insulin caused problems for people allergic to pigs Disadvantages * is still being tested with mice * yoghurt would need to be eaten regularly to replace bacteria
Insulin - The Dude That's Friends With THE DUDE
Genetically engineered insulin may have fewer side effects than the insulin previously extracted from the pancreases of other animals. This is because genetic engineering inserts human genes such as the gene for insulin production into the DNA of bacteria. As a result, the bacteria that produces human insulin, when used by diabetics, should produce fewer side effects.
E. coli that contains the gene for human insulin is genetically engineered, transgenic, and a GMO. Bacteria have been engineered to produce chymotrypsin, make human insulin, produce enzymes that increase shelf life of bread, and to produce enzymes that improve the taste and clarity of beer.
Insulin can come from a number of sources. It is sometimes extracted from the pancreas of a pig, but it can also be made by genetically engineered bacteria. So for a particular batch of insulin, you would have to find out how it was made.
E. coli can be genetically engineered to produce insulin through the introduction of the gene encoding insulin. This allows the bacteria to synthesize and secrete insulin protein, which can then be harvested and used for medical purposes, such as treating diabetes.
Yes, human insulin can be produced through genetically engineered organisms, such as transgenic bacteria or yeast. These organisms are modified to express the human insulin gene, allowing them to produce insulin that is identical to the insulin produced by humans.