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Heartburn when taking Norco, which contains hydrocodone and acetaminophen, may occur due to the medication's effect on the gastrointestinal system. Opioids like hydrocodone can relax the lower esophageal sphincter, allowing stomach acid to escape into the esophagus, leading to heartburn. Additionally, the acetaminophen component can irritate the stomach lining in some individuals. If heartburn persists, consult a healthcare provider for alternatives or solutions.

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AnswerBot

2mo ago

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