Mitochondria are needed in order to supply the energy for the active transport of sodium ions out of the cells in the proximal tubule to create a concentration gradient which allows more sodium ions to enter the cell from the luminal side.
Water passively follows the sodium out of the cell along its concentration gradient.
- proximal tubule : • Selective reabsorption of nutrients from filtrate back into blood by active and passive transport. • Within proximal tubule, pH is controlled by secretion of hydrogen ions (H1) and reabsorption of bicarbonate ions (HCO32). - distal tubule • Selective reabsorption of nutrients from blood into nephron by active transport. Distal tubule helps regulate potassium (K1) and salt (NaCl) concentration of body fluids. • As in proximal tubule, pH is controlled by tubular secretion of hydrogen ions (H1) and reabsorption of bicarbonate ions (HCO32).
insufficient NaCl reabsorption due to high GFR -- After glomerular filtration, NaCl is actively reabsorbed at many locations along the renal tubule. If the filtrate is moving through the tubule quickly, less reabsorption is possible, so more NaCl gets left behind. This means that at the JGA, the NaCl concentration within the filtrate will be high.
insufficient NaCl reabsorption due to high GFR -- After glomerular filtration, NaCl is actively reabsorbed at many locations along the renal tubule. If the filtrate is moving through the tubule quickly, less reabsorption is possible, so more NaCl gets left behind. This means that at the JGA, the NaCl concentration within the filtrate will be high.
renal corpuscle and renal tubule
Water without NaCl.
In the ascending loop, Na+ (or any solute) is actively pumped out of the tubule. As flow continues up the loop, the tubular concentration decreases as does the interstitial (the fluid surrounding the loop) concentration.Because water is impermeable in the ascending loop, the volume at the bottom of the loop is the same as that entering the distal tubule. At the bottom of the loop, the tubular and interstitial concentrations are equal.The ascending loop of Henle actively pumps sodium and potassium out but water can not follow. This concentrates the water inside the loop of Henle.
High concentration of NaCl in the renal tubule at the juxtaglomerular apparatus (JGA) is likely to trigger the release of renin, a hormone that plays a key role in regulating blood pressure and kidney function. This response is part of the renin-angiotensin-aldosterone system, which helps to maintain blood pressure and electrolyte balance in the body.
Sodium chloride is a solute when is dissolved in water (the solvent).
The enthalpy of dissolution of NaCl in water is the amount of heat energy released or absorbed when NaCl dissolves in water.
The Macula Densa cells in the kidney respond mainly to changes in the sodium chloride (NaCl) concentration in the tubular fluid. They help regulate the body's blood pressure and fluid balance by sensing NaCl levels and signaling for adjustments in kidney function.
NaCl in water is a mixture.
NaCl is added to water when a saline water solution is necessary; NaCl is dissociated in water: NaCl -------------------Na+ + Cl-