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Antibodies are usually made in response to being exposed to an antigen. If you have had measles, then you have made antibodies to that antigen. Next time you are exposed, your body will fire up the antibodies and you will defeat the antigen (measles) quickly. You may feel some thing. You might say "I am coming down with something" but it will pass quickly.

In RBC, the genetic make up of the blood gives antibodies for each type. These are already in the plasma. There are antigens on each type of RBC.

1. Type A blood has antigen A on it's surface while antibody B is in the plasma. This person can be given A and a bad reaction will not occur as there is no antibody A in the plasma.

2. Type B has antigen B and antibody A in the plasma. Type B blood can be given but not A.

3. Type O has both antigens A and B and no antibodies for A or B. Only O can be given.

4. Type AB has no antigens on it's surface and both antibodies A and B. Types O, B, A, and AB can be given.

It is always desirable to give the same blood type. However, if it is very necessary, O can be given to all other blood types. It is called the universal donor.

AB can take any other blood type and is called the universal recipient.

To further complicate things RBCs also have an Rh factor and are called Rh+.

If not they do not, they are Rh-. These also should match. However O- is the actual universal donor.

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11y ago

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