How can a person have no corpus callosum and has no history of neurological problems?

Answer 1

Agenesis of the Corpus Callosum does not occur because of other neurological problems but may occur in conjunction with other disorders. Often when it does occur with other anomalies of the brain, the disorder of the corpus callosum is overlooked. Individuals may have complete agenesis (C-ACC), partial agenesis (P-ACC) or a disorder of the corpus callosum (DCC) such as it may be thin. Researchers at the University of California, San Francisco have found that approximately 1:4,000 people have a disorder of the corpus callosum. The exact cause has not been determined because but the condition is frequently seen in individuals with fetal alcohol syndrome or genetic anomalies. Deletions of specific genes have been associated with ACC; approximately 20% of all individuals with a corpus callosum anomaly have a chromosomal duplication or deletion.