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The absence of the respiratory system would affect the circulatory system - blood could not be oxygenated; consequently the tissues of the body cannot be supplied with oxygen. This means that the tissues and organs cannot perform their functions and would die due to lack of oxygen. Furthermore, deoxygenated blood would accumulate; so carbon dioxide levels would increase. This decreases the pH (increases acidity) of the blood and the lungs are responsible for regulating this.

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