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How can translocation occur as the result of the onset or causing a disease like cancer?
Translocation in the context of cancer occurs when a segment of DNA is relocated from one chromosome to another, often leading to genetic mutations that can drive tumorigenesis. This can happen when DNA breaks and reattaches improperly during cell division or in response to environmental factors such as radiation or chemicals. These chromosomal rearrangements can activate oncogenes or inactivate tumor suppressor genes, contributing to uncontrolled cell growth and the development of cancer. Such genetic alterations are critical in the progression of various cancers.
What else can I help you with?
What is significance of translocation?
Translocations can result into gene dysregulation, thus leading to diseases like cancer.
Is sickle-cell disease a result of a translocation?
No. It arises due to point mutations (like A -> T).
Is prader-willi syndrome a result of translocation?
According to the research I've done, Prader-Willi Syndrome is rarely a result of translocation, but it is a possibility. Translocation in this syndrome results in an inactivation of genes on the paternal chromosome 15.
What is caused by chromosomal translocation?
Chromosomal translocation can lead to genetic disorders and cancer. It can result in the fusion of genes from different chromosomes, creating abnormal gene products that may interfere with normal cellular functions. This can disrupt gene expression and lead to the development of various health conditions.
How many people a year in US die from smoking?
None. People don't die from smoking:People die from cancer and other forms of lung disease resulting from smoking.People die from heart disease as a result of smoking.People die in fires as a result of burning cigarettes causing trash can fires or fires in bed.
Is cancer the number one killer in U.S.?
No, heart disease is number one. Cancer is 2nd, however. Though Cancer is statistically the #2 killer and nearly tied with Heart Disease, Cancer actually far surpasses Heart Disease in the U.S. as a result of how statistics are gathered. It is very common for someone who has died as a result of cancer to actually have stated on their death certificate something other than cancer (i.e. kidney failure, internal bleeding, etc). Something to consider.
Damage to the genetic material in your skin cells can result in a serious disease called?
Osteoparosis
Which std is caused by hpv?
HPV is a sexually transmitted disease that can result in warts, or certain types of cancer.
What disease can occur is the cell cycle doesn't happen correctly?
Cancer is a result of a malfunctioning cell cycle.
What disease do the mechanisms that normally control the cell cycle are disrupted?
The cell cycle is disturbed when a mutation causes one or more of the following:A deletion - causing a section of the DNA to be missingA stop - causing a stop signal to form in the DNAA frame shift - causing the DNA sequence to be misaligned
What is transfer of genes between nonhomologous chromosomes?
Transfer of genes between nonhomologous chromosomes is known as chromosomal translocation. It can result in the fusion of two chromosomes or the exchange of genetic material between them. This process can lead to genetic abnormalities and diseases.
When part of the one chromosome breaks off and is added to a different chromosome the result is a?
Translocation
