This occurred due to the fact that the first manufacturer of thalidomide was a German pharmaceutical company - which first sold this drug in October of 1957. This was followed by British approval of the drug. Subsequently, over the next ten years or so, about 2,500 "thalidomide babies" were born in Germany, and about 2,000 in Great Britain. The birth defect is called phocomelia, a shortening of the limbs, in which they appear to look like the flippers on a seal.
Also, the FDA did not approve thalidomide in the U.S. (although quite a few tablets found their way to the U.S., despite the FDA ban).
Thalidomide caused severe birth defects in babies whose mothers took the drug during pregnancy. These birth defects included limb deformities, such as missing or malformed limbs, as well as other malformations of organs like the ears, heart, and digestive system. Thalidomide exposure during pregnancy led to a tragic and widespread public health crisis in the 1950s and 1960s.
Thalidomide was supposed to be an effective sedative for pregnant women, but thalidomide caused birth defects and peripheral neuropathy.
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Thalidomide was marketed as an aid for nausea and for pregnant women to prevent morning sickness. Thalidomide was withdrawn because it was found to cause birth defects in newborns, such as missing limbs, it also caused peripheral neuropathy (nerve damage) in long time users. Thalidomide still being used as a treatment option for various forms of cancer.
Congenial deformities are given at birth. You are to be born with the deformity for it to be considered as congenial.
Yes - there are thousands of deformed people as proof of the Thalidomide trials ! The drug Thalidomide was initially marketed as a cure for 'morning sickness' associated with early pregnancy. HOWEVER - the drug also caused deformities in the developing embryos, resulting in mental an physical abnormalities. There was a huge legal battle to get the makers of Thalidomide to accept responsibility for the flaw in their product. See the related link to Wikipedia for a detailed article on the drug - and its consequences.
Thalidomide, a drug initially prescribed for morning sickness in pregnant women during the late 1950s and early 1960s, caused severe birth defects in babies, including limb malformations, organ abnormalities, and facial deformities. Known as phocomelia, the most notable effect was the underdevelopment of arms and legs. The tragedy led to stricter regulations on drug testing and approval for pregnant women. Today, thalidomide is used under strict controls for certain conditions, but it remains a poignant reminder of the importance of drug safety.
Thalidomide is a drug that was prescribed to pregnant women in the 60's ish to relieve the symptoms of morning sickness that was later discovered to cause birth deformities (particularly malformed limbs). -a sedative and hypnotic drug; withdrawn from sale after discovered to cause severe birth defects because it inhibits angiogenesis -Thalidomide is a sedative-hypnotic, and multiple myeloma medication. The drug is a potent teratogen in rabbits and primates including humans -A drug that was sold during the late 1950s and 1960s as a sleeping aid, and to pregnant women as an antiemetic to combat morning sickness and ... -tranquilizing drug that can have a teratogenic effect on the auditory system of the developing embryo when taken by the mother during pregnancy ... -A drug being investigated for its potential as an angiogenesis inhibitor. -An emblematic example of a chemical applied to health. Its use in treating sickness during pregnancy in the 1960s resulted in birth defects. The birth defects were caused because thalidomide changes the growth and development of new blood vessels (angiogenesis) in the developing babies. ... -A drug rarely used because of its disastrous side effects in pregnancy, but proving useful in some lupus with severe skin lupus. -A drug to help morning sickness that was withdrawn in 1961 after it was found to cause limb deformities in babies born to women who had taken it -drug which is a powerful human teratogen. First synthesized in Germany in 1954 as a new antihistamine, the drug was found to be a safe.
yes it will cause birth deformities in the babies chest and facial region. Can also cause downs and spinal meningitis, stillbirth, and miscarriage
There is no treatment for Thalidomide. It is a birth deformity caused by the drug Thalidomide, taken during pregnancy. The treatment is NOT to take Thalidomide. It has obviously been banned, since finding the connection between it and birth defects in the 1950's. With modern levels of political correctness, those that suffer from birth defects are treated very well and with respect. Most sufferers manage to adapt to their circumstances very well and lead mostly normal lives. The defects are not genetic and sufferers can have normal offspring.
It might cause Birth defects in women who are pregnant or women who might get pregnant in the future. It has caused really bad birth defects in the past, and it would probably do so in the future if women who are capable of bearing children are exposed to it.
Doctors often prescribed Thalidomide to pregnant women to treat morning sickness and as a sedative to assist with sleep. Thalidomide was sold from 1957 until 1961. The product was withdrawn when it was discovered that Thalidomide was teratogenic - causing malformations of an embryo or foetus. Countless babies were born with birth-defects; most notably missing limbs.