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There is no definitive diagnosis of Morgellons disease other than its classification as either nonspecific dermatitis or delusional parasitosis.

Morgellons sufferers display fibrosis from external or internal sources, coupled with a sensation of subdermal movement or itching. A CDC study concluded that there was no identifiable pathogen or parasite in the majority of cases. Where topical skin treatments do not stop the symptoms, some patients responded to antipsychotic drugs, which reduced anxiety over the sensations felt. Antibiotics and anti-inflammatory drugs are sometimes successful in treating lesions and sores, but can be harmful if used over long periods of time.

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