How do you get valuim out of your body?

Answer 1

Valium belongs to the class of benzodiazepine sedative used for treating anxiety. It is the longest acting drug in the class. It is converted in the body to another chemical which is actually the active drug.

It is made more water soluble by the liver and then excreted through the kidneys. 98% of it sticks to proteins in the blood (ie albumin) and only the 2% in solution is active, so you have to take a lot of the drug to get an effect, then there is a large quantity of inactive drug sticking to the proteins. It may take two weeks taking the pill every day before the drug reaches its maximum effect. This delayed effect can be a problem, especially in elderly patients.

It is released slowly from the proteins. It has a half-life of 20 to 70 hours. This is a wide range because liver function varies between individuals and tends to decline with age. That means that if you stop taking the drug, the amount in the blood will drop to half in 20-70 hours. For example, in an older person the half-life is about 72 hours or 3 days and it will take 3 days to get to half the level, 6 days to get to 1/4th the level and 9 days to get down to 1/8th.

What can you do to accelerate this process? Not much. You could take or eat something else that sticks to blood proteins such as aspirin. This would bump some of the Valium off the proteins and increase blood levels. That would increase its rate of excretion by the kidneys, but the higher blood level would make the drug more active so I would not recommend it. You are better just to wait for your body to do its own thing slowly! Drinking more does not alter the rate of excretion by the kidneys (glomerular filtration rate is not affected by drinking more).