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What questions might scientists have asked following the discovery of cyclin?
Scientists might have asked how cyclin levels are regulated during the cell cycle, what specific role cyclin plays in regulating cell division, and whether abnormalities in cyclin expression or function are associated with diseases like cancer.
Where can you buy cyclin from?
Well dah!!! Were everyone else gets cyclin from the cyclin store!
What happens to the Cdk-cyclin A complex at metaphase?
Both cyclin A and Cdk remain undegraded
Which cyclin forms the primary Cdkc that controls the G2 stage?
Cyclin B forms the primary Cyclin-dependent kinase complex (Cdkc) that controls the G2 stage of the cell cycle. Cyclin B-Cdk complex plays a crucial role in regulating the progression from the G2 phase to mitosis by phosphorylating specific target proteins.
What is the relationship between cancer and cells?
All cancer is related to the cell cycle. The cell cycle is the cycle of events and regulations that occur through the life of a cell. Part of the cell cycle is cell division. This process needs to be carefully regulated, because un-controlled cell division is called cancer. There are molecules within a cell that respond to signals and stimuli from the envoronment to decide is the cell is allowed to divide. These pathways relay mostly on cyclin and cyclin-dependent kinases. If the regulations fail in a cell - in this case, a skin cell - then you have a cencerous condition in the tissue - in this case, skin cancer.
What is M-cyclin?
M-cyclin is a type of cyclin protein that is involved in regulating the cell cycle. It works in conjunction with cyclin-dependent kinases to drive the progression of cells through different phases of the cell cycle. M-cyclin specifically plays a key role in controlling the transition from G2 phase to mitosis.
What substances form the cyclin-cyclin dependent kinase combinations that control the stages in the cycle?
proteins and enzyme
What causes the decrease in the amount of cyclin at a specific point in the cell cycle?
The decrease in cyclin levels at a specific point in the cell cycle is typically caused by the cyclin being targeted for degradation by ubiquitin-mediated proteolysis. This process is regulated by the activity of specific enzymes called ubiquitin ligases, which mark the cyclin for destruction by the proteasome. This decrease in cyclin levels is important for progression to the next phase of the cell cycle.
What is a protein synthesized at specific times during the cell cycle that associates with a kinase to form a catalytically active complex?
Cyclins are proteins that are synthesized at specific times during the cell cycle and associate with cyclin-dependent kinases (CDKs) to form a catalytically active complex. This complex regulates the progression of the cell cycle by phosphorylating specific target proteins.
How is cyclin concentration regulated?
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What causes the MPF complex to initiate mitosis in the cell cycle?
The MPF complex is activated by the phosphorylation of its Cyclin B subunit by Cyclin-dependent kinase (Cdk), causing the complex to become active and initiate mitosis. This phosphorylation is regulated by various factors such as growth factors, DNA damage, and regulatory proteins within the cell cycle.
What part of the body does skin cancer generally affect?
cancer
