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Charcot-Marie-Tooth disease (CMT) primarily affects the peripheral nerves, leading to muscle weakness and atrophy, especially in the feet and legs. It can cause sensory loss, resulting in decreased ability to feel pain or temperature changes, and may lead to foot deformities like high arches or hammertoes. Over time, individuals may experience difficulties with balance and coordination. The severity and specific symptoms can vary widely depending on the type of CMT.

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5mo ago

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Is CMT a genetic disease?

Charcot-Marie-Tooth disease (CMT), also known as Charcot-Marie-Tooth neuropathy, hereditary motor and sensory neuropathy (HMSN) and peroneal muscular atrophy (PMA) - is a genetically and clinically heterogeneous group of inherited disorders of the peripheral nervous system characterised by progressive loss of muscle tissue and touch sensation across various parts of the body. Currently incurable, this disease is one of the most common inherited neurological disorders affecting approximately 1 in 2,500 people equating to approximately 23,000 people in the United Kingdom and 125,000 people in the USA. CMT was previously classified as a subtype of muscular dystrophy.


What is the hard surface of tooth made of?

The hard surface of the tooth is made of enamel which is the hardest tissue in the human body. Tooth enamel has no living cells so unlike a broken or fractured bone the body has no way to repair chipped/cracked enamel.


What part of your body are canines?

They are a type of tooth.


The strongest substance in your body is?

Enamel of the tooth.


What parts of your body start with i?

incisor (Tooth)


What do you call the white covering of the tooth?

It is called the enamel. It's the most external layer of a tooth and the hardest substance in the body.


Hardest material in the human body?

Tooth enamel.


What is the internal body cavity?

An internal body cavity is a space in the body that does not contain something, much like a cavity in a tooth is where the tooth has rotted away. There are several examples of this: your sinuses are internal body cavities - they are an open space in your body. There is a body cavity in your chest as well surrounding your lungs and heart.


What effect does mummification have on the body?

the effect is to preserve the body for millions of years


What is the effect of the salt on the body?

The effect is to dry the flueds inside the body


What all in the body does Fluoride effect?

Fluoride primarily affects the teeth by strengthening tooth enamel and helping to prevent tooth decay. When ingested, fluoride can also accumulate in bones and help to increase bone density. However, excessive fluoride intake can lead to dental fluorosis, a condition that affects the appearance of the teeth.


Tooth is the strongest bone in human body?

No, the femur or thigh bone is the strongest bone in the human body.

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