Let's start by defining thrombosis- it refers to a lump or plug of a blood clot, usually occurring in a vein.* It also, refers to the clotting process and forming of the clot. Clotting is a complex step-by-step process that involves many different stages and ingredients. If something goes wrong with one or more of these steps, the clotting process can be overactive or under active; making the blood too thick (with clotting and plugging tendencies) or too thin (bleeding time is increased and it is difficult to stop the loss of blood.) Factor V Leiden refers to a disorder where one of those ingredients causes the blood to clot abnormally, making the blood 'thick' and too likely to clot too quickly, with resulting thrombosis. This disorder runs in families and is suspected when the family has a history of blood clots in the veins. My dear niece has this disorder and her life was saved by a board-certified hematologist, when other physicians could not figure out what was wrong with her and her life was in jeopardy. She is thriving today and has learned to manage this disorder in her daily life. *Veins are 'slow highways' that return blood back to the heart, and arteries are the 'fast highways' that carry oxygen-rich blood pumped out of the heart.
After the age of 14 I was told, this is around the time when the blood starts to thicken in everyone, but obviously more with Factor V Leiden.
Thrombosis is the medical term meaning abnormal condition of blood clots.Thrombosis is the medical term meaning condition of blood clots. A generic condition resulting in increased likelihood of producing blood clots is called a hypercoagulable disorder.Most people will develop blood clots under certain conditions, such as after surgery, sometimes after long trips, or with certain conditions which cause you to be more likely to have blood clots - pregnancy, taking birth control pills, etc.Clotting is predisposed when any of three conditions are present: endothelial injury, stasis, or hypercoagulability. These three conditions together are called Virchow's triad.There are certain hypercoagulable disorders that are heritable. These include antithrombin III deficiency, thrombin gene mutation, anticardiolipin antibody, lupus anticoagulant, Factor V Leiden deficiency, Protein C or S deficiency, and methyltetrahydrofolate reductase (MTHFR) deficiency.All these conditions predispose a person to develop venous thrombosis, and if several DVTs develop, the person may need to be on lifelong anticoagulation with warfarin to prevent pulmonary emboli and pulmonary hypertension.Thrombrosis.
A light blue-top tube with sodium citrate is typically used to collect blood for Factor V Leiden testing, as citrate is an anticoagulant that prevents blood clotting during processing.
Simply put. No. If you have Factor V Leiden, you are contraindicated for taking any estrogen...be it birth control, estrogen therapy or hormone therapy. As far as progestin only pill........my doctors have told me no for that as well.
Leiden law school is part of Leiden University, Leiden, The Netherlands. Leiden is a smallish city between the Hague and Amsterdam. It is also a great nickname for a girl that lives in the philippines.
Leiden is in Europe.
John of Leiden died in 1536.
The area of Leiden is 23.16 square kilometers.
Leiden University was created in 1575.
Siege of Leiden happened in 1573-10.
Deep vein thrombosis (DVT) and pulmonary embolism (PE) can be influenced by various clotting factors, but one key factor is Factor V Leiden. This genetic mutation leads to resistance against activated protein C, resulting in an increased tendency for abnormal blood clotting. Other contributing factors include prothrombin gene mutations and deficiencies in natural anticoagulants like protein C, protein S, and antithrombin. These factors can result in a hypercoagulable state, increasing the risk of thrombus formation.
Being heterozygous for Factor V Leiden means having one copy of the gene mutation, which increases the risk of developing abnormal blood clots. It is a genetic condition that can increase the risk of blood clots in veins, especially in situations such as pregnancy or surgery. Treatment and management strategies aim to reduce the risk of clotting events.