How does hemophilia spread in your body?

Answer 1

Depending on the definition of carrier you're using the answer is yes or no.

Definition 1: An individual with a genetically linked disorder whom, while showing no signs or symptoms of the disorder, can pass the genetic disorder to their children.

Answer:

In this case, the answer would be no. If a male has a genetic mutation for hemophilia, he would show the signs and symptoms. Since the trait is located on the X chromosome and males only have one X chromosome there would be no choice but to demonstrate that trait.

Definition 2: An individual with a genetic disorder whom can pass that disorder on to their children.

Answer:

In this case, the answer would be yes. Males will pass the genetic mutation on to their daughters but since they pass their Y chromosome on to their sons, not the X, males cannot pass the genes to their sons.

Answer 2

Hemophilia is a hereditary (X-linked, recessive) blood disorder that affects the proper clotting of blood. It is a disease that affects males much more frequently (1 in 10,000) than females (1 in 100,000,000). This occurs because a critical blood-clotting gene is carried on the X chromosome. So because males carry only one X chromosome, if it is defective he will have hemophilia. Females, on the other hand, carry two X chromosomes. If only one is defective, the other normal X chromosome can compensate. The woman will have normal blood clotting, but she will still be a carrier of the recessive defective gene. A woman will know if she is a carrier sooner through genetic testing or later if any of her children are hemophiliacs. Naturally, female hemophiliacs are rare because it takes two defective X chromosomes in order for the condition to occur. Women with the recessive gene that codes for hemophilia simply pass it on to their offspring. Resource-www.knowledgene.com Written by: Aaron Nazarian and Idan Ivri

Answer 3

Hemophilia is transferred by X chromosome. This being the recessive gene, females are usually the carriers. The other normal X chromosome does not allow the expression of the gene. So this disease is seen in males only, practically. The patient will transfer the gene to his daughter, who will be carrier. Patient will not transfer the gene to his son, as son will not get the X chromosome from his father.

Answer 4

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Answer 5

Hemophilia is an X-lined recessive disease. It is caused by a mutation of the F8 gene as in hemophilia A, and F9 gene as in hemophilia B.