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MHC I

MHC I is present in all cells except red blood cells (they lack nuclei). MHC I will present an intravesicular antigen to the cells surface for it to be identified as self or foreign by your adaptive immunity cells.

MHC II

MHC II is present in professional antigen presenting cells which include: macrophages, B cells and dendritic cells. These cells will engulf bacteria, soluble proteins, viruses, etc. Whatever was taken into the cell becomes processed in the increasingly acidic endosome that eventually will cut the antigen into peptides. MHC II transported from the ER will meet up with this endosome and the peptides will bind to MHC II for it to eventually present on the cells surface.

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The specific foreign substances that an individuals immune system has the ability to recognize and resist is detemined by?

The immune system's ability to recognize and resist specific foreign substances is determined by the unique set of proteins on the surface of cells called major histocompatibility complex (MHC) molecules. MHC molecules present antigens to immune cells, which stimulate the immune response. The immune system can only respond to antigens that are recognized by MHC molecules.


A marker molecule on a cell that the immune system uses to recognize a pathogen?

The major histocompatibility complex (MHC) molecules are marker molecules on cells that the immune system uses to recognize pathogens. MHC molecules present fragments of pathogens on the cell surface to alert immune cells to the presence of the pathogen. This helps the immune system to target and eliminate infected cells.


Four of the five cells listed - viruses cells - MHC markers - cancer cells - bacteria - dead cells - are targets of the immune system - Select the exception?

MHC markers- which are proteins that present or "show" antigens like bacteria to other immune cells. Instead of being targets, they are helper proteins of the immune system.


What is the function of MHC?

Major histocompatibility complex (MHC) molecules play a critical role in the immune system by presenting antigens to T cells. This helps the immune system distinguish between self and non-self molecules and initiate an immune response against foreign invaders. MHC also plays a role in tissue compatibility during organ transplantation.


The MHC is important in?

MHC is important in adaptive immunity. It provides your adaptive immunity, T cells, processed antigens so that it can decide whether what your cell has is a foreign substance that needs to be destroyed or if it is self that needs to be left alone.


Major histocompatibility complex mch is important in?

The major histocompatibility complex (MHC) is important in the immune system for presenting antigens to T cells. It plays a crucial role in distinguishing self from non-self molecules and triggering immune responses against foreign invaders such as pathogens. MHC molecules are highly polymorphic, allowing for a diverse immune response to a wide range of antigens.


What is the role of MHC?

Major Histocompatibility Complex (MHC) molecules play a crucial role in the immune system by presenting antigens to T cells. This helps T cells identify and respond to foreign invaders such as viruses or bacteria. MHC molecules are essential for adaptive immune responses and play a key role in determining compatibility for organ transplants.


Class you MHC genes code for?

MHC genes code for the Major Histocompatibility Complex proteins. These proteins are essential for the immune system to distinguish self from non-self antigens and help in the presentation of antigens to T cells. The MHC genes are highly polymorphic, giving rise to diverse MHC proteins that enable recognition of a wide range of pathogens.


When MHC will be expressed?

MHC I and MHC II are always expressed. The antigen it presents on a cells surface can be foreign or it can be self. It is the T cell that determines whether what the MHC is displaying is self or not. Remember antigen can be protein, lipid, sugars, etc.


Do cancer cells have MHC?

Absolutely not.Major histocompatibility complex (MHC) is a cell surface molecule encoded by a large gene family in all vertebrates. MHC molecules mediate interactions of leukocytes, also called white blood cells (WBCs), which are immune cells, with other leukocytes or body cells.


Do T cells express MHC II?

No, T cells do not express MHC II. MHC II molecules are primarily found on antigen-presenting cells, such as dendritic cells, macrophages, and B cells, and are involved in presenting antigens to T cells for immune responses. T cells, on the other hand, express MHC I molecules, which present antigens to other immune cells.


The MHC is important in a T cell's ability to?

The major histocompatibility complex (MHC) is important in a T cell's ability to recognize antigens presented by antigen-presenting cells. This recognition is crucial for initiating an immune response and coordinating the functions of different immune cells. Deficiencies in MHC expression or function can impact the ability of T cells to mount an effective immune response.