by ocular fluid outflow
Pilocarpine is a cholinergic agonist that stimulates muscarinic receptors in the eye, leading to miosis (pupillary constriction) and increased aqueous humor outflow, lowering intraocular pressure. This mechanism of action is beneficial in treating conditions like glaucoma.
Intraocular pressure above 21 mmHg is considered elevated and may be harmful to the eye. Prolonged high intraocular pressure can damage the optic nerve, leading to conditions such as glaucoma. It is important to monitor and control intraocular pressure to prevent vision loss.
The procedure performed to check the intraocular pressure of the eye is called tonometry. This test measures the pressure inside the eye and is commonly used to screen for glaucoma.
Normal intraocular pressure is between 10 and 20 mmHg. I've also seen 15.5 +/- 2.75.
Increases in intraocular pressure can be caused by conditions such as glaucoma, uveitis, eye trauma, and certain medications. These conditions can lead to a buildup of fluid (aqueous humor) in the eye, which raises the pressure inside the eye.
The aqueous humor in the eye helps to maintain proper intraocular pressure by providing nourishment to the eye's tissues, regulating the pressure within the eye, and removing waste products.
Pilocarpine lowers the heart rate.
The major known cause of glaucoma is a relative increase in intraocular pressure, or IOP. The purpose of glaucoma treatment, whether medical or surgical, is to lower the IOP.
Tonometry measures intraocular pressure (i.e. checks for glaucoma).
Obstruction of the canal of Schlemm can lead to increased intraocular pressure, which may result in glaucoma. Glaucoma can cause damage to the optic nerve and potentially lead to vision loss if left untreated. Treatment may include medications, laser therapy, or surgery to reduce intraocular pressure and prevent further vision loss.
The purpose is to lower intraocular pressure in the treatment of glaucoma.
Tonometry is the test that measures intraocular pressure.