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Temperature affects how the enzymes work in your body. Enzymes are proteins that catalyze (i.e. incraese the rates of) chemical reactions in living cells. If it gets too hot or cold the enzymes might denature and lose the shape of their active site, which means the substrate may no longer fit and this decreases the rate of the chemical reactions. Moreover, if the temperature is too high one may start to sweat in order to evaporate some of the heat off their skin. If too much water is lost through sweating, one may become dehydrated and experience a variety of symptoms. If the temperature is too cold, one may begin to shiver in order to gain heat, which uses energy from respiration. One may also experience hypothermia.

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