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They FIRE, when a SUFFICIENT stimulus is received.

A neuron can receive a stimulus from a SENSORY INPUT, or from ANOTHER NEURON.

When a SENSORY NEURON is stimulated by some physical event, such as touch, sound, light, etc, sensory receptors on the neurons cell membrane translate the physical stimulus into electrical impulses by causing changes in the balance or proportions of electrically charged IONS.

When a neuron is stimulated by ANOTHER NEURON, the stimulating neuron (or, "pre-synaptic" neuron) has released NEUROTRANSMITTER chemicals into the space between the two neurons (the SYNAPSE), as a consequence of its own activation (firing); the neurotransmitters then bind to receptors on the post-synaptic neuron, usually on a DENDRITE, causing Sodium ion pores to open, which allow Sodium ions to enter the neuron which has now been "stimulated". These Sodium ions then electrostatically "bump" other Sodium ions, which bump others, etc, along the dendrites and cell body (soma), in a process called ELECTROTONIC CONDUCTION, which has the property of happening quickly, but looses strength as it moves along. When this impulse reaches the beginning of the neurons AXON, at a location called the AXON HILLOCK, this impulse is summed or added with any other similar impulses, and if it reaches a THRESHOLD value, it will cause the axon to FIRE, which means that a slightly different (but still ionically electrical) neural impulse will be generated along the axon, called an ACTION POTENTIAL.

And the original answer to this question was:

Neurons send vital messages to the brain so it can decide what to do.

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