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The RAAS system involves several organs. When there is a loss of blood or loss of fluid and blood pressure falls, the liver produces angiotensinogen. The kidney produces renin which acts as an enzyme to change angiotensinogen into angiotensin I.

The kidneys along with the lungs produce a enzyme called ACE which changes angiotensin I into angiotensin II.

Angiotensin II is a vasoconstrictor which acts on the vascular system to increase blood pressure. It also acts on the pituitary gland. The pituitary gland produces ADH. ADH means antidiuretic hormone. It causes the kidneys to "hold onto" water. The kidney produces aldosterone as a result, causing the body to conserve sodium.

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