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This has to do with acid-base homeostasis. Normal blood pH is 7,4.

- Alkalosis = pH >7,4

- Acidosis = pH <7,4

Then you have 2 types for each one, respiratory or metabolic.

- Respiratory alkalosis = CO2 <40mmHg

- Respiratory acidosis = CO2 >45mmHg

- Metabolic alkalosis = HCO3- >26mEq

- Metabolic acidosis = HCO3- <22mEq

If your breathing rate goes beyond 20 per minute (hyperventilation), CO2 goes down and pH goes up. Then your body compensates this by losing HCO3- in the urine, lowering the pH.

If your breathing rate slows down below 15 per minute (hypoventilation), CO2 goes up and pH goes down. Then you reabsorb more HCO3- in the kidneys, raising the pH.

If your kidneys start malfunctioning, your body can't excrete acid compounds and HCO3- gets consumed, then the pH goes down. Your breathing rate goes faster in order to excrete more CO2, raising the pH.

And in some cases the kidneys reabsorb more HCO3- than they should, and pH goes up. Then your breathing rate slows down, CO2 goes up and pH goes down.

In some cases, pH can vary due to other reasons, such as Diabetes or diarrhea, which can produce acidosis, or severe vomiting, that produces alkalosis. These are classified as metabolic as well, but can be regulated both by the respiratory and the urinary system, though the latter is rather inefficient in these cases.

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