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Wilson disease is also called hepatolenticular degeneration, referring to its effects on the liver ("hepato-") and lenticular nucleus (part of the basal ganglia of the brain). The disease is due to an inability to transport copper, and so deposits accumulate in several areas, including the lenticular nucleus, causing damage. The lenticular nucleus, which comprises the globus pallidus and putamen, is part of the brain's basal ganglia, and damage to it can give signs and symptoms of Parkinson disease. Other signs of parkinsonism may also be apparent in patients with Wilson disease; these include dementia and mood disorders.

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