How hyperkalemia is treated with salbutamol?

Answer 1

Salbutamol, a beta-2 adrenergic agonist, is used in the treatment of hyperkalemia because it promotes the uptake of potassium into cells, thereby lowering serum potassium levels. The mechanism involves stimulation of beta-2 receptors, which leads to increased activity of the sodium-potassium ATPase pump. This effect is typically rapid but temporary, making salbutamol a useful adjunct treatment alongside other therapies like insulin and glucose or calcium administration. It is particularly beneficial in acute hyperkalemic situations, such as in patients with renal failure or severe acidosis.