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Mono tests include:
• Monospot test. This quick screening test detects a type of antibody (heterophil antibody) that forms during certain infections. A sample of blood is placed on a microscope slide and mixed with other substances. If heterophil antibodies are present, the blood clumps (agglutinates). This result usually indicates a mono infection. Monospot testing can usually detect antibodies 2 to 9 weeks after a person is infected. It typically is not used to diagnose mono that started more than 6 months earlier.



• EBV antibody test. For this test, a sample of blood is mixed with a substance that attaches to antibodies against EBV. A series of tests can detect different types of antibodies to help determine whether you were infected recently or sometime in the past.

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7y ago
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13y ago

If mononucleosis is suspected, a physician will typically conduct a physical examination, including a "Monospot" antibody blood test that can indicate the presence of proteins or antibodies produced in response to infection.

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13y ago

Mononucleosis usually is diagnosed by a blood test--called a mono spot test--that measures anti-bodies to EBV.

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Q: How is mononucleosis diagnosed?
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