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Some forms of malaria can cause death rapidly, following on from the incubation period of 2-4 weeks.

P. flaciparum malaria can manifest as cerebral malaria, and cause death in as few as 2 hours. Otherwise, falciparum will cause death in about a week or so.


Other forms of malaria (vivax, oval) follow less progressive courses, and otherwise health adults may not die from the disease.


The person who is infected should also be considered, with death more likely to occur in small, malnourished children than in healthy people. Iron deficiency may also have a protective influence on those in endemic areas. The effects of malaria may also be reduced in those people who have sickle cell disease, or sickle cell trait.

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