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Previous answer: I think it's about 42 degrees, although 3 years ago, I contracted blood poisoning and my temp went up to 42.3, the doctors were amazed i was still alive.

Temperatures above 40 degrees Celsius or 104 degrees Fahrenheit are life-threatening. Brain damage or brain death often occur at temperatures of 41 degrees Celsius or 106 degrees Fahrenheit as this is when the brain begins to be damaged by the high temperature.

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