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As many as necessary, depending on patient. On an elderly patient, or a patient with significant other co-morbidities (other health problems) which would not be 'cured' by a liver transplant, the surgery could be considered more risky (i.e higher risk of death). If the surgery was considered very high risk (e.g elderly patient with a significant heart problem), some hospitals may not consider doing the re-transplant operation. However, if the patient is still expected to have a good quality of life after (however many) re-transplants, re-transplanting will still be considered, and is usually performed. (Typically, the patient will give up having transplants before the hospital refuses to perform them.) The main problem with re-transplanting is build up of scar tissue around the site - this leads to high levels of blood loss during surgery, which makes each successive re-transplant higher risk than the previous. But it is not impossible to live a normal life after a few liver re-transplants :)

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