Is albinism polygenic

Answer 1

Albinism is primarily caused by mutations in specific genes responsible for melanin production, such as TYR, OCA2, and TYRP1, indicating that it is not strictly polygenic. While multiple genes can influence the various forms of albinism and their associated traits, the condition itself is typically classified as a monogenic disorder due to its direct link to mutations in single genes. However, the expression of albinism can be affected by environmental and genetic factors, which adds complexity to its inheritance.