Is it possible to have a germ free tongue?

Answer 1

As in sterile? No way. The mouth is just too perfect an environment for microbe growth. It is warm, dark, moist, and it has a good food supply.

You can reduce the bacterial load on the tongue through effective oral hygiene practices and perhaps through the use of antimicrobial rinses, but it is highly unlikely you could ever get a tongue to be completely free of bacteria.

The only exception is a newborn infant before their first meal. Their mouths are usually germ free. Once milk or formula is introduced, the bacteria are present and multiplying.

On the upside, the normal flora (microbes) that inhabit a 'clean' mouth are not harmful.