It depends on the reason that cylinder is misfiring. It could cause serious damage to the catalytic converter.
You buckle up and you drive safe
Drive around with it for a while and let us know.
never
It is not safe to call or text while driving.
my 2002 ford escape sensor is misfiring and it won't shift into drive
The opposite of drive safe is careless driving.
You can but it is not a good idea. If your engine is misfiring then unburnt fuel will enter the exhaust. This will damage the O2 sensor and eventually destroy the catalytic converter costing you big time. Stop driving the car until you can have it repaired.
most likely misfiring cylinder(s) and/or worn engine mounts.
A safe thing to do while driving on long, straight stretches of highway on a sunny day?
it is safe to drive slower because you could get in a car accident if you drive really fast
A dodge neon is safe to drive.