Is noyes Whitney equation applcable for invivo?

Answer 1

The Noyes-Whitney equation is primarily used to describe the dissolution rate of solid substances in a solvent, typically under controlled laboratory conditions. While it can provide insights into in vivo dissolution processes, its direct application in vivo is limited due to the complex biological environment, including factors like physiological conditions, fluid dynamics, and biological interactions. Thus, while it may offer a theoretical framework, empirical validation in vivo is necessary for accurate predictions.