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In patients with colon or rectal cancer, the p53 gene is mutated 70% of the time

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14y ago

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What was Gene Watson's illness?

Gene Watson's illness was colon cancer according to recent articles.


Is there a cancer susceptibility gene found for colon cancer?

Yes, there are several forms of familial colon cancer. Several mutations are associated with multiple colon polyps that can be diagnosed with a colonoscopy. This trait is called "Familial adenomatous polyposis". Other mutations are not associated with polyps; the trait is called "hereditary non-polyposis colorectal cancer".


How long do people live with colon cancer?

People usually live from two to three years with colon cancer, but this is only the most likely answer. Cancer sometimes comes from the genes of relatives. In other cases you can have gene mutation and another possibility is by putting carcinogens in your body.


Why would you get cancer of the pancreas?

Check the link below. It appears that it is often related to gene mutations.


Is colon cancer dominant or recessive?

Colon cancer is not classified as either dominant or recessive. Instead, it is considered a complex disease influenced by multiple factors, including genetic, environmental, and lifestyle factors. Genetic Factors: While some cases of colon cancer can be linked to specific genetic mutations that are inherited in a dominant or recessive pattern, many cases are due to a combination of genetic variations that increase the risk of developing the disease. For example, mutations in genes such as APC, MLH1, MSH2, MSH6, PMS2, and STK11 can increase the risk of hereditary colorectal cancer syndromes, such as familial adenomatous polyposis (FAP) or Lynch syndrome (hereditary nonpolyposis colorectal cancer, HNPCC). Environmental and Lifestyle Factors: Environmental factors such as diet, physical activity, smoking, alcohol consumption, and exposure to certain carcinogens can also significantly influence the risk of developing colon cancer. Lifestyle choices and environmental exposures can interact with genetic predispositions to increase or decrease the risk of developing the disease. Complex Inheritance: The inheritance pattern of colon cancer is complex and varies depending on the specific genetic mutations involved. Some mutations may follow an autosomal dominant pattern, where inheriting a single copy of the mutated gene from one parent can increase the risk of developing cancer. In contrast, other mutations may follow a recessive pattern, requiring two copies of the mutated gene (one from each parent) to significantly increase the risk. Therefore, colon cancer is better understood as a multifactorial disease influenced by a combination of genetic, environmental, and lifestyle factors, rather than being classified as strictly dominant or recessive in inheritance.


How could gene therapy be used to treat cancer?

With the help of Gene therapy we can replace or supress the cancer gene


Can women carry the prostate cancer gene?

No, the prostate cancer gene is only found in men.


What did Gene Upshaw die from?

Gene Upshaw died from pancreatic cancer in 2008 at the age of 63.


Why is the A-T gene one of the most important cancer-related genes?

an estimated 1% (2.5 million in the United States) of the general population carries defective A-T genes. Carriers of one copy of this gene do not develop A-T, but have a significantly increased risk of cancer


What disease can a gene mutation cause?

usually cancer


What is a malignant gene?

A malignant gene is a gene that has mutated and is involved in promoting cancer growth and progression. These genes can be oncogenes, which promote cell proliferation, or tumor suppressor genes, which normally inhibit cell growth but are inactivated in cancer.


What is the term for a cancer gene?

Oncogene.