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1. skin and mucous membraneThe first line of defense is a surface protection composed of anatomical and physiological barriers that keep microbes from penetrating sterile body compartments.2.White Blood Cells (leukocytes) The second line of defense is a cellular and chemical system that comes immediately into play if infectious agents make it past the surface defenses.

3.Immunity

The third line of defense includes specific host defenses that must be developed uniquely for each microbe through the action of specialized white blood cells.a. natural
  • active- occurs when you get a disease
  • passive- received from the mother's placenta or milk

b. acquired/artificial

  • active- when a vaccine is give (VACCINE- a dose of weakened living or dead virus/bacteria
  • passive- when you are given a dose of antibodies produced by either people or animals that you were exposed to or had a similar disease
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