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Mycosis fungoides is due to invasion of the skin by T cells. These are normally a form of white blood cells called lymphocytes that are involved in the immune system but in this condition are behaving abnormally.

The condition starts as inflamed (erythematous) scaly patches on covered areas of the skin, the buttocks, thighs or trunk. These may last for several years. Untreated they may form tumours from which the name 'mushroom like' fungoides come. This is, however, extremely rare these days.

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Mycosis fungoides, a type of cutaneous T-cell lymphoma, primarily involves malignant T lymphocytes known as CD4+ T cells. These abnormal cells accumulate within the skin, causing a variety of skin lesions. In advanced stages, the disease may spread to other organs such as the lymph nodes, blood, and internal organs.


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