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Leukemia patients suffer from a deficiency of platelets, among deficiencies of normal blood cells.

Platelets are important clotting factors. A lack of platelets in the blood results in hypocoagulability. This predisposes patients to hemorrhages (bleeding diathesis). This means that if a leukemia patient suffers from external or internal trauma, they tend to bleed really easy.

What i don't get is this- what about patients who did not suffer from any injury? Do they still bleed spontaneously? What causes them to bleed? There must be something damaging the blood vessels or causing an increase in endothelial gaps (allowing passage of red blood cells) before blood actually appears in the nose or mouth, right? Is high blood pressure such a cause and what other causes are there?

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13y ago

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