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Blood platelet levels are sometimes seen in alcoholics and may be caused by an alcohol-induced enlarged spleen (splenomegaly), folate (one of the B vitamins) deficiency, but most frequently, a direct toxic effect of alcohol on production, survival time, and function of platelets. Platelet count begins to rise after 2 to 5 days' abstinence from alcohol. The alcohol-induced condition is generally reversible with abstinence, and clinically significant hemorrhage is rare.

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