No, it is not.
G6PD (Glucose-6-Phosphate-Dehydrogenase) is an enzyme which protects the red blood cells under specific circustances.
These specific circumstances include
- certain drugs/medications (sulfonamides, antimalarial drugs, salicylates)
- diet (fava beans)
- infections
- fever
- acidosis.
Individuals, born with a deficiency of this enzyme, are not efficiently protected. Meaning, if they are subjected for a longer time to any of these specific substances or conditions, their unprotected red blood cells could suffer damage. Due to this damage, the red blood cells are destroyed - leading to bleeding (hemolytic episodes).
This inborn deficiency is X-linked, which means, it primarily effects males, partial involvement or carrier situation applies to females.
This aspect is similar to that of Thalassemia, as Thalassemia is also an inherited condition, which effects males primarily, and females are mainly the carriers.
But, G6PD is a deficiency of an enzyme (Glucose-6-Phosphate-Dehydrogenase), and Thalassemia is caused by a genetic fault, which impairs the synthesis (production) of haemoglobin, the red blood cells' oxygen-carrying molecules.
While G6PD deficiency is active only at the above specific circumstances, Thalassemia is constantly present.
The usual cause of abnormal hemolysis in newborn is blood group incompatibility between mother and baby either Rh or ABO. Other causes are much less common-hereditary spherocytosis, thalassemia, G6PD deficiency etc.
Alpha thalassemia silent carrierAlpha thalassemia minor, also called alpha thalassemia traitHemoglobin H diseaseAlpha thalassemia major, also called hydrops fetalisBeta thalassemia minor, also called beta thalassemia traitBeta thalassemia intermediaBeta thalassemia major, also called Cooley's anemia or beta-zero (ß0) thalassemiaBeta-plus (ß+) thalassemiaMediterranean anemia
Can you be around fire works if you have g6pd
Thalassemia is an autosmal recessive blood disease. That means that it is an inherited disease. Thalassemia in more common in Mediteranian people.
Yes, A "carrier" of alpha thalassemia and of beta thalassemia can marry, but not to someone with any hemoglobinopathy. Prof. Kornfeld Pal
No
Yes. Direct DNA testing and sequencing of the G6PD gene are possible, and there is also a fast an inexpensive test called the "Beutler flourescent spot test" that can be performed on the blood of a patient suspected of having G6PD.
No. A minor form of the blood disorder thalassemia is when you inherited just one beta thalassemia gene, along with a normal beta-chain gene. This manifests as mild anaemia with a slight lowering of the hemoglobin level in the blood. No treatment is require. By contrast, a thalassemia major, also known as Cooley's Disease, is when one is born with two genes for beta thalassemia and no normal beta-chain gene. This is a serious disorder.
The most significant consequence of this disorder is hemolytic anemia, which is usually episodic, but the vast majority of people with G6PD deficiency have no symptoms.
Tramadol is not on the list of contraindicated drugs for those with G6PD. Remember to always tell your doctor and pharmacist that you are G6PD Deficient and have them verify that the medicine is allowable for your use. An answer of 'probably' isn't really acceptable from a doctor making $300 an hour ;)
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no