Skeletal muscle fatigue is primarily attributed to a combination of factors, including the depletion of energy substrates (like ATP and glycogen), the accumulation of metabolic byproducts (such as lactic acid), and impaired calcium handling within muscle fibers. Additionally, changes in the nervous system's ability to stimulate muscles can contribute to fatigue. These factors together hinder muscle contraction efficiency and reduce overall performance during prolonged or intense physical activity.
Depends on the circulatory system
The condition in which there is diminished tone of the skeletal muscle is hypotonia.
Fatigue
Myocitis.
It is called muscle fatigue.
Fatigue of skeletal muscle may result from a variety of factors, including depletion of energy stores such as ATP and glycogen, accumulation of metabolic byproducts like lactic acid, and disruption of calcium ion homeostasis. Additionally, neurotransmitter depletion at the neuromuscular junction can contribute to muscle fatigue. Prolonged or intense muscle activity can also lead to oxidative stress and damage to muscle fibers, further exacerbating fatigue.
SKELETAL (:
Muscle fatigue
Muscle fatigue
skeletal muscles
smooth muscle, cardiac muscle and most glands
Skeletal muscle