Microscopic examination of the affected muscle would show the following changes:
A. degenerating skeletal muscle fibers (i.e. "cells").
B. proliferation of endomysium connective tissue around the degenerating muscle cells.
C. numerous macrophages (i.e. scavenger white blood cells) in the area, whose job it is to clear the cellular debris in the damaged muscle tissue.
D. while some of the muscle fibers are breaking down (as seen in a cross section), other fibers appear to be dense (or dark in color). These latter cells are presumably in a state of excessive contraction (i.e. more overlap between actin and myosin), probably because other segments of these cells (not in the microscopic viewing field) are experiencing breakdown of the cell membrane. Destruction of the cell membrane would of course, allow calcium ions to flow into the cell from the extracellular fluid (down their electrochemical gradient). As calcium floods the interior of these cells, it binds to troponin and causes a shift in tropomyosin, thus exposing the globular head binding sites on actin. Cross-bridges form and, in the muscle cell's "last breath," it contracts.
In muscular dystrophy, creatine kinase (CK) levels are typically significantly elevated, often ranging from 5 to 50 times higher than the normal range. Normal CK levels are usually between 30 to 200 U/L, so those with muscular dystrophy may have CK levels exceeding 1,000 U/L. This elevation occurs due to muscle damage and breakdown associated with the condition. However, CK levels can vary based on the specific type of muscular dystrophy and the individual's age and activity level.
The three basic parts of a typical urine examination are physical examination (color, clarity, odor), chemical examination (testing for specific compounds like glucose, protein, and ketones), and microscopic examination (analyzing urine sediments for cells, crystals, and other particles).
There are 210 calories in a typical Hershey's chocolate bar.
A typical solution is a homogeneous mixture with only one phase; a suspension is a nonhomogeneous mixture.For a colloid the answer is more complicate: the appearance is homogeneous, single phase but at a microscopic scale the system is not homogeneous.
typical of him
Kate Winslet because she has the body of a typical healthy female. She is not too small and not too big, nor is she too muscular. She also has curves like a women should have and doesn't deprive herself from food when her body needs it.
Typical: the ordinary
whta is typical meromoreis
She ordered her typical morning coffee with cream and sugar.
Her nervous system is still developing and forming bonds with the muscular system. You will be lucky if she make write a few letters of the alphabet before five. After all, the human brain doesn't fully develop before the age of 25.
4 is a typical number
The typical is the average