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Spain primarily settled in the Caribbean, Central America, and parts of South America. Key areas included present-day Mexico, where Hernán Cortés conquered the Aztec Empire, and the Andes region, where Francisco Pizarro overthrew the Inca Empire. Additionally, Spanish explorers established colonies in the southern United States and along the Pacific coast, such as in California and Florida. Their influence spread widely, resulting in a significant cultural and political legacy throughout these regions.

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