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The skin is home to a diverse population of normal flora, primarily consisting of bacteria such as Staphylococcus, Corynebacterium, and Propionibacterium, which can number in the millions per square centimeter. Various factors can alter the levels of these microorganisms, including changes in skin pH, moisture, temperature, the use of antibiotics, and skin conditions such as eczema or acne. Additionally, lifestyle factors like hygiene practices and diet can also influence the composition and abundance of skin flora. Disruptions to this balance can lead to skin infections or other dermatological issues.

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