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Being burned can vary in severity - the biggest concerns are fluid loss and infection. Severe and extensive tissue damage caused by burns can also severely lower blood albumin levels, which can make drug overdose easier, since there isn't as much blood albumin to bind the drugs. Lung tissue damage is also possible if the burn victim were to breath in the flames. The worst possible after effect of being on fire would be death, either through fluid loss, infection, asphyxiation, or heat related organ failure.

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