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  • Predominantly female. Additional risk factors include lower educational and/or occupational achievement, head injury, Down's syndrome, low estrogen levels, and family history of the disease. Risk of developing Alzheimer's Disease (AD) doubles every 5 year after the age 65. Incidence of non-familial form of AD in one's 60s is 0.6%, in 70s is 2.0%, and in 80's 10.2%. With the familial form of AD, a person may develop the disease as early as in his/her 20s. The chance of inheriting the familial form of AD is 50-50.

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