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This is a big question, but here's the basics:

During the growth of the embryo, three main tissue types are formed: Endoderm, Mesoderm and Ectoderm. Each one of these tissue types is responsible for the formation and function of all the organs and tissues in your body. As the embryo matures, additional tissue types are maturing as well. Why does this matter to the question? Well, even though there are hundreds of subtypes of cancer, all can be traced back to one of the six (some say seven) tissues identified below:

Epithelium (Skin and lining cells (like the inside of your mouth or stomach)

Mesenchymal (cartiledge, tendons, etc)

Lymphatic (White blood cells)

Neronal (Nerves and support cells for the nervous system)

Melanocytes (Skin pigment producing cells)

Neuroendocrine (Pancreas, adrenals, etc)

Each one of these tissue types can give rise to the following cancers in the order given above:

Carcinoma

Sarcoma

Lymphoma

Neuroma

Melanoma

Neuroendocrine (aka Carcinoid)

From these basic six cancers, all others are related. Rhabdomyosarcoma, for example, sounds big and complicated, but it's root, -sarcoma, tells us that it's a cancer of the mesenchymal tissues (in this case, a skeletal muscle tumor).

For a more complete list of cancers, I'd recommend a copy of Robbin's Pathologic Basis of Disease.

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13y ago

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