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Dyskinesias typically improves by what percentage post-pallidotomy?

Dyskinesias typically improve by 75% or more.


How are tics distinguished from other dyskinesias?

One of the major clinical signs that help distinguish tics from other dyskinesias is the presence of involuntary ocular (eye) movement in persons affected with tics.


How effective is pallidotomy in helping tremors?

Studies show the surgery generally improves tremor, rigidity, and slowed movements by 25-60%. Dyskinesias typically improve by 75% or more.


What are the downsides of using the drug levodopa to treat Parkinson's disease?

Unfortunately, levodopa becomes less effective over time, and also produces unwanted and uncontrolled movements called dyskinesias.


What drug treatment complications are common in PD patients?

Including rapid wearing off of drug effect, unpredictable "off states" (times of low levodopa levels in the blood), and disabling dyskinesias.


What is the mode of action for amantidine in treating parkinson's disease?

Amantidine is a dopamine facilitator and it acts by increasing dopamine release in basal ganglia.


What would happen if the extra pyramidal system was damaged?

Damage to the extrapyramidal system can result in movement disorders such as Parkinson's disease, dystonia, or dyskinesias. Symptoms may include tremors, rigidity, slowness of movement, and difficulty with motor control and coordination. Treatment may involve medications, physical therapy, and in some cases, deep brain stimulation.


What are the side effects of dopamine agonists?

Side effects of dopamine agonists can include nausea, dizziness, fatigue, and hallucinations. These medications may also increase the risk of impulse control disorders such as gambling or hypersexuality. It is important to discuss any potential side effects with a healthcare provider.


Why would doctors use depakote with a parkinson's patient?

Doctors may use Depakote (valproate) with a Parkinson's patient to help manage symptoms such as tremors, muscle rigidity, and dyskinesias. Depakote is an anticonvulsant that can also have mood-stabilizing effects, which may be beneficial for Parkinson's patients who experience mood disturbances. Additionally, Depakote has been studied for its potential neuroprotective properties, which could be beneficial in slowing the progression of Parkinson's disease.


What to sperm consist of?

The spermatozoon is a remarkably complex metabolic, locomotive and genetic machine. It is approximately 60 microns in length and is divided into 3 sections: head, neck and tail. The oval sperm head consists of a nucleus containing the highly compacted DNA, and an acrosome that contains the enzymes required for penetration of the egg shell for fertilization. The neck maintains the connection between the sperm head and tail and consists of the connecting piece and proximal centriole. The tail harbors the midpiece, principle piece and endpiece. The tail midpiece contains the axoneme or engine of the sperm and the mitochondrial sheath, the source of energy for movement. Physiologically, the sperm axoneme is the true motor assembly and requires 200-300 proteins to function. Among these, the microtubules are the best-understood components. Sperm microtubules are arranged in the classic "9+2" pattern of 9 outer doublets encircling an inner central doublet. Defects in the sperm axoneme are well-recognized causes of ciliary dyskinesias that are routinely associated with infertility.


Parkinsonism levodopa carbidopa?

nausea and vomiting low blood pressure, particularly when standing up, resulting in dizziness and fainting dyskinesias (abnormal movements including twisting and tics) in at least 50% of patients agitation hallucinations


Your 38 year old son takes Prozac and risperdal and recently you have noticed he curls his 345 fingers towards his palm Does this combination of drugs dause this to happen?

Risperidone (Risperdal) is an antipsychotic medication, and as such, there are are many side effects including those that effect motor contol."People taking antipsychotic drugs are at risk of developing certain side effects known as extrapyramidal symptoms. These symptoms can include things such as repetitive, involuntary muscle movements (such as lip smacking) or an undeniable urge to be moving constantly. Fortunately, there is help for these symptoms. Let your healthcare provider know right away if you develop any of these symptoms while taking an antipsychotic medication."Extrapyramidal symptoms are usually divided into different categories. Dyskinesias are movement disorders, while dystonias are muscle tension disorders. "Tardive" symptoms are those that appear during long-term treatment (often after several years). Unlike earlier symptoms, tardive symptoms are more likely to be permanent even after the medication is stopped.It is important for your son to make his doctor aware of any side effect he may experience as soon as possible. His doctor can determine if the symptom is medication related or if there is an underlying problem occurring His doctor can then weigh the risks vs. benefits of your son continuing his current medication regime. Good luck to you both. Anne (RN)