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Organ failure, bleeding, lack of breathing, and infection.

Chronic use:

You can damage your liver and kidneys from chronic use.

You can cause a stomach bleed from an ulcer, and bleed out over time.

You can cause an infection from the stomach ulcer. Alcohol also depresses your immune system which can make fighting infections harder.

Acute use:

You can become so drunk that you depress your nervous system to the point where it cannot breathe on it's own. This is rare.

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