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Kidney enzymes are enzymes specific to the kidney.

Enzymes are protein molecules that speed up (or catalyze) chemical reactions in the body. These chemical reactions serve a wide variety of functions, many involving the production of special molecules in the body. Some of these molecules are produces relatively exclusively by the kidney. To limit the production of these molecules to the kidney requires that only the kidney contains the necessary enzymes needed to produce these molecules. These enzymes would logically be called kidney enzymes.

An example of a molecule produced relatively exclusively by the kidney is calcitriol, the active form of vitamin D3. Calcitriol is produced through a chemical reaction catalyzed by the kidney enzyme 25-hydroxyvitamin D3 1-α-hydroxylase (also called 1α-hydroxylase).

One enzyme that is made by the kidneys is renin. It is part of the renin-angiotensin mechanism that helps regulate blood pressure.

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