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Is there any genotype that is SC?
Yes, the genotype SC refers to individuals who have inherited one sickle cell allele (S) and one C allele, resulting in a sickle cell trait that is different from having sickle cell disease. This genotype can lead to some symptoms similar to sickle cell disease under certain conditions.
How is sickle-cell disease a representation of codominance?
It's not sickle-cell itself, but rather being a heterozygous carrier of the disease. People with one dominant and one recessive allele for the disease are immune to malaria without the crippling effects of having sickle-cell anemia. I don't think that it can even represent codominance, though.
Do carriers of sickle cells get simptoms of the disease?
Carriers of sickle cell disease, known as sickle cell trait, typically do not experience symptoms of the disease. They usually have one normal hemoglobin gene and one sickle hemoglobin gene, which means they can produce both normal and abnormal hemoglobin. While they are generally asymptomatic, under extreme conditions such as high altitude or severe dehydration, some carriers may experience mild symptoms. However, they do not have the full-blown disease, which primarily affects individuals with two sickle hemoglobin genes.
What are the symptoms of the sickle cell trait?
Some of the symptoms that come with sickle cell trait can include fever, as well as an acute form of cell degeneration that can happen throughout the body.
What groups get sickle cell disease?
A person can only inherit sickle-cell genes if some of their ancestors came from certain regions in Africa where the inhabitants carry sickle-cell genes. A person with one sickle-cell gene has sickle-cell trait, a milder problem. If both father and mother pass on sickle-cell genes, the child, with two genes, will have sickle-cell disease.
People who are heterozygous for sickle cell disease are generally healthy because of what?
People who are heterozygous for sickle cell disease possess one normal hemoglobin gene and one sickle hemoglobin gene, which allows them to produce enough normal red blood cells to prevent symptoms of the disease. This condition, known as sickle cell trait, provides some protection against malaria, as the presence of sickle hemoglobin can interfere with the parasite's life cycle within red blood cells.
Top 10 questions asked about sickle cell?
What is sickle cell disease?Sickle cell disease is an inherited disorder that affects red blood cells. People with sickle cell disease have red blood cells that become hard and pointed instead of soft and round. Sickle cells cause anemia, pain and many other problems.Top2) What is sickle cell trait?If you have sickle cell trait, you have inherited the gene for sickle cell disease. Sickle cell trait does not turn into sickle cell disease. If someone has sickle cell trait and his partner has sickle cell trait they may produce a child with sickle cell disease. There are about 2.5 million people in America with sickle cell trait.Top3) If sickle cell trait is not an illness, why are people tested?Babies are tested to see if they have sickle cell disease. Teens and adults are tested mainly to see if they can have a baby with the disease.Top4) What medical problems are caused by sickle cell disease?Lung tissue damage, pain episodes and stroke. The blockage of blood flow caused by sickled cells also causes damage to most organs including the spleen, kidneys and liver.Top5) How many people have sickle cell disease?Sickle cell disease is a global health problem. In the United States it is estimated that over 70,000 people have sickle cell disease. About 1,000 babies are born with the disease each year in America.Top6) How long does a person with sickle cell disease live?The average life expectancy in America has improved. It is now in the mid 40 years of age range.Top7) Are people of African descent the only group affected?No. It is also present in Portuguese, Spanish, French Corsicans, Sardinians, Sicilians, mainland Italians, Greeks, Turks and Cypriots. Sickle cell disease also appears in Middle Eastern countries and Asia.Top8) Is there a cure?There is no universal cure for sickle cell disease. Research in gene therapy, the ultimate universal cure, is currently underway.Top9) What are some promising treatment developments?The use of hydroxyurea has shown promising results on some adult sickle cell patients. It reduces the frequency of severe pain, acute chest syndrome and the need for blood transfusions.Top10) Can people with sickle cell disease live a productive life?Yes. But like all patients with chronic disease, sickle cell patients are best managed in a comprehensive multi-disciplinary program of care and a strong extended support system.
Is coffee good for sickle cells?
Coffee contains antioxidants and may offer some health benefits; however, its effects on sickle cell disease are not well-established. Some studies suggest that caffeine could potentially improve blood flow, but excessive consumption might lead to dehydration, which can exacerbate sickle cell symptoms. It's essential for individuals with sickle cell disease to consult their healthcare provider for personalized advice regarding coffee and overall diet.
What are some genetic diseases?
one genetic disease is sickle cell disease. another is thallasemia.
How can sickle cell be both recessive and incomplete dominance?
Sickle cell disease is primarily a recessive disorder, meaning that an individual must inherit two copies of the sickle cell gene (one from each parent) to express the disease. However, it also exhibits incomplete dominance because individuals with one normal gene and one sickle cell gene (carriers) can show some symptoms, such as mild anemia or sickle-shaped cells under certain conditions. This dual expression illustrates how the sickle cell trait can manifest in varying degrees depending on the genetic makeup of the individual. Thus, while the disease is recessive, the trait displays incomplete dominance in heterozygous carriers.
What is the difference between thalassemia and sickle cell anemia?
Though Thalassemia and Sickle Cell Anemia are seemingly similar to the unknowing, a large difference remains; Thalassemia is characterized by a reduced production from one of the globin chains which make up hemoglobin while in Sickle Cell Anemia, the globin chains themselves are structurally defective.
If Natasha has normal blood cell but marries someone who has sickle cell trace What are the chances of them having a child with sickle cell?
If a person does not carry the Sickle cell trait and they marry some one with the trait. The child that comes from that relationship can never have sickle cell disease, however that child has a chance of having the sickle trait.
