diarrhoea, dermatitis, dementia, death
Pellagra can be cured by taking nicotinamide. The nicotinamide can be found in pill form and will reverse the condition of pellagra.
Pellagra is historically associated with poverty and malnutrition, so countries where these conditions are prevalent may experience cases of pellagra. This includes regions in Africa, parts of Asia, and some areas in the United States.
he knew in the south every had pellagra
Pellagra is not an infectious disease. Pellagra is a nutritional deficiency disease.
Primary pellagra results when the diet is extremely deficient in niacin-rich foods.
Dr.Goldberger did an experiment to see what caused pellagra
Dr.Goldberger did an experiment to see what caused pellagra
Untreated pellagra will continue progressing over the course of several years, and is ultimately fatal.
Pellagra primarily affects adults, particularly those between the ages of 30 and 60, although it can occur in individuals of any age, including children. It is often associated with diets low in niacin (vitamin B3) and protein, and is more prevalent in populations with limited access to diverse food sources. People with certain medical conditions or those who abuse alcohol may also be at higher risk for developing pellagra.
The physician Dr. Gaspar Casal first described pellagra in the 18th century. However, the definitive link between diet and pellagra was made by Dr. Joseph Goldberger in the early 20th century.
The 4 D's of pellagra are dermatitis (skin rash), diarrhea, dementia (mental confusion), and ultimately death if left untreated. Pellagra is caused by a deficiency of niacin (vitamin B3) in the diet.
The evidence that pellagra was not caused by a germ primarily comes from the observation that the disease's prevalence was closely linked to diet rather than infectious transmission. Researchers, notably Dr. Joseph Goldberger, demonstrated that pellagra could be prevented and treated with a diet rich in niacin (vitamin B3) and proteins, which was lacking in the diets of those affected. Additionally, the disease did not spread in a typical infectious manner, as outbreaks were associated with specific socioeconomic conditions rather than person-to-person contact. This led to the conclusion that pellagra resulted from nutritional deficiency rather than a germ.